Functional, environmental, genetic and congenital factors are considered as main etiological causes of craniofacial asymmetry. Studies showed that asymmetric function or body posture may induce asymmetric malocclusion and mandibular growth. Progressive exacerbation of the asymmetry with secondary maxillary involvement and canting of the occlusal plane frequently occur.
The efficacy and predictability of the functional therapy as an adjunct for treatment of craniofacial asymmetry will be illustrated, as early treatment with functional appliances intends to induce symmetric function, accelerate growth of the affected side, prevent the characteristic dento-alveolar compensations and obviate early major surgical interventions.