The development of 3D imaging tools for diagnosis and treatment planning is one of the most exciting developments in orthodontics as well as in oral and maxillofacial surgery in the 21st century. The applications of 3D imaging in orthodontics include pre- and post-orthodontic assessment of dentoskeletal relationships and facial aesthetics, auditing orthodontic outcomes, 3D treatment planning, 3D soft and hard tissue prediction and essential information for clinicians to better manage impacted teeth. 3D imaging methods expand and deepen our understanding of growth and development and therapy, and benefit for orthodontists and patients in future.