The purpose of this study was to evaluate the influence of different buccal corridors and buccal-lingual inclinations of canines and posterior upper teeth on smile aesthetics; to correlate the preference for these inclinations on the different sizes of buccal corridors; and to determine if esthetic perception is the same when evaluated in face or smile images. A facial photograph was obtained and three different sizes of buccal corridors were digitally created, an increased buccal corridor with 14%; an intermediate with 7% and a decreased with 1% per side. Three different buccal-lingual inclinations for canines and posterior teeth were also created, 10º lingual, 0º and 10º buccal. These images were evaluated by orthodontists, aesthetic dentists and laymen (n=30 for each group) using an analogic visual scale. Scores were compared by two-way ANOVA for repeated measures for all groups. The intermediate buccal corridor was considered more attractive and the decreased buccal corridor was less attractive for all groups (p<0.001). Canines and posterior teeth with no inclination or with lingual inclination were considered attractive, while buccal inclination of these teeth was rejected by all groups (p<0.001). Aesthetic dentists gave lower scores to all images, while laymen gave higher scores than orthodontists. Teeth with buccal inclinations had a negative influence on attractiveness for the different sizes of buccal corridors. The intermediate buccal corridor positively influenced buccal-lingual inclinations. The orthodontists suffered least influence from the face when evaluating smile aesthetics, whilst laymen suffered more influence from this factor.