Many congenital anomalies exhibit phenotypes of impaired maxillofacial growth and function, which may often threaten quality of life (QOL) of the patients. Japanese government has recently modified the policy to secure the rights of a wider scope of anomaly patients to undergo orthodontic treatment through health insurance system. In addition, contemporary molecular biological research has delineated genetic and epigenetic alterations of specific genes as a cause of various congenital anomies. Hence, with all these circumstances, the precise diagnosis and quality orthodontic care are now accessible to the patients with more ease.
Our experience and knowledge in the clinic and research laboratory regarding congenital anomalies will be shared in this presentation.