The aim of this presentation is to describe and illustrate the orthodontics therapy of patients with missing maxillary lateral incisors ( space opening and space closure ). Missing teeth are one of the most common developmental problems in children and can occur in an isolated fashion, or as part of a syndrome. The term hypodontia is used when one to six teeth ( excluding third molars )are missing, and oligodontia when more than six teeth are absent ( excluding third molars ). Anodontia is an extreme case, denoting complete absence of teeth. Any tooth in the arch can be congenitally absent. Treatment of missing teeth require careful planing with with particular reference to the orthodontic considerations. A number of factors complicate treatment options. Orthodontic treatment for patients with congenitally missing teeth is a challenge to effective treatment planning. The two major alternatives, orthodontic space closure ( 1.case report ) or cpace opening ( 2. case report )for prosthetic replacements,implantation or autotransplantation, can both compromise aesthetics, periodontal health and function.